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CPM
Models
Contributed Examples
CPM
One Random Walker
Morpheus Model ID:
M2003
Unbiased and biased random walkers Introduction We can simulate the swimming motion of a cell, such as a bacterium, by interspersing short periods of directed motion with random turns or random scrambling of the cell’s velocity.
L. Edelstein-Keshet
(Author)
Y. Xiao
(Contributor)
L. Edelstein-Keshet: Mathematical Models in Cell Biology
Models
Contributed Examples
CPM
CPM Parameter Plane
Morpheus Model ID:
M2001
Two-parameter plane showing all possible regimes of behavior for a single CPM cell Introduction The idea is based on figure 3 in the referenced paper. Description But here, we use two dimensionless parameters:
L. Edelstein-Keshet
,
J. Starruss
(Authors)
D. Jahn
,
Y. Xiao
(Contributors)
L. Edelstein-Keshet: Mathematical Models in Cell Biology
Models
Contributed Examples
CPM
Two CPM Cells Adhesion
Morpheus Model ID:
M2006
Example demonstrating how adhesion energies affect cell shape and the cell-cell contact region Introduction We simulate two CPM cells of the same type to demonstrate how adhesion energies affect cell shape and the cell-cell contact region.
L. Edelstein-Keshet
(Author)
Y. Xiao
(Contributor)
L. Edelstein-Keshet: Mathematical Models in Cell Biology
Selected Publications
Unraveling the effect of intra- and intercellular processes on acetaminophen-induced liver injury
In high dosages, acetaminophen (APAP) can cause severe liver damage, but susceptibility to liver failure varies across individuals and …
M. M. Heldring
,
A. H. Shaw
,
J. B. Beltman
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Code
DOI
Model
Selected Publications
Reoccurring neural stem cell divisions in the adult zebrafish telencephalon are sufficient for the emergence of aggregated spatiotemporal patterns
Regulation of quiescence and cell cycle entry is pivotal for the maintenance of stem cell populations. Regulatory mechanisms, however, …
V. Lupperger
,
C. Marr
,
P. Chapouton
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DOI
Model
Selected Publications
Self-organized multicellular structures from simple cell signaling: a computational model
Recent synthetic biology experiments reveal that signaling modules designed to target cell-cell adhesion enable self-organization of …
N. Mulberry
,
L. Edelstein-Keshet
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DOI
Model
Selected Publications
Heterogeneous, delayed-onset killing by multiple-hitting T cells: Stochastic simulations to assess methods for analysis of imaging data
Although quantitative insights into the killing behaviour of Cytotoxic T Lymphocytes (CTLs) are necessary for the rational design of …
R. J. Beck
,
D. I. Bijker
,
J. B. Beltman
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DOI
Model
Selected Publications
A dynamic cell recruitment process drives growth of the Drosophila wing by overscaling the vestigial expression pattern
Organs mainly attain their size by cell growth and proliferation, but sometimes also grow through recruitment of undifferentiated …
L. M. Muñoz-Nava
,
H. A. Alvarez
,
M. Flores-Flores
,
O. Chara
,
M. Nahmad
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DOI
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