Size

Now we finally arrive at the 3D model. As an example, we further develop the coupled PDE and CPM model with mechanical interaction. Similar to the 1D to 2D case, it is straighforward to extend the dimensionality to 3D.

Introduction This example model cell fate decisions during early patterning of the pancreas (de Back et al., 2012). The simple gene regulatory network of each cell is coupled to adjacent cells by lateral (juxtacrine) signaling.

The migration of zebrafish polster cells is oriented by the migration of follower cells, allowing robust long-range coordination of different cell populations. Introduction Collective cell migration is an important process during biological development and tissue repair.